Lisinopril Dosage

Typical Lisinopril Dosages ¹-

Usual Adult Dose for High Blood Pressure-
Initial dose:  10 mg orally once a day, in patients not receiving a diuretic.
Maintenance dose:  20 to 40 mg orally once a day.
Some patients appear to have a further response to 80 mg, but experience with this dose is limited.

Usual Adult Dose for Congestive Heart Failure-
Initial dose: 5 mg orally once a day (If on diuretic, the diuretic dose should be reduced).
Maintenance dose:  5 to 20 mg orally once a day.

Usual Adult Dose for Myocardial Infarction-
Initial dose:  5 mg orally (within 24 hours of the onset of acute myocardial infarction).
Subsequent doses:  5 mg orally after 24 hours.
10 mg orally after 48 hours.
Maintenance dose:  10 mg orally once a day. Dosing should continue for six weeks.
Patients with a low systolic blood pressure (<=120 mm Hg) when treatment is started or during the first 3 days after the infarct should be given a lower 2.5 mg oral dose of lisinopril.  If hypotension occurs (systolic blood pressure <=100 mm Hg) a daily maintenance dose of 5 mg may be given with temporary reductions to 2.5 mg if needed.  If prolonged hypotension occurs (systolic blood pressure <90 mm Hg for more than 1 hour), lisinopril should be withdrawn.

Usual Adult Dose for Diabetic Nephropathy-
Initial dose:  10 to 20 mg orally once a day.
Maintenance dose:  20 to 40 mg orally once a day.
Dosage may be titrated upward every 3 days.

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