Lisinopril Side Effects

Lisinopril for Blood PressureLisinopril is an ace inhibitor used primarily used to treat high blood pressure. Lisinopril is the generic version of Zestril® and Prinivil.

Lisinopril is used as a treatment for  people with high blood pressure; congestive heart failure and recent heart attack sufferers.
These are the breakdowns of side effects for each category of patients 1


High Blood Pressure – The following side effects occurred in more than 1% of patients:

  • Coughing (most common)
  • Body weakness (asthenia)
  • Dizziness, lightheadedness, or fainting
  • Fatigue
  • Extreme low blood pressure
  • Diarrhea
  • Nausea
  • Vomiting
  • Headache
  • Dizziness

Lisinopril is generally well tolerated with adverse effects occurring in approximately 5.7% of patients, according to clinical trials.


Congestive Heart Failure(CHF)- The following side effects occurred in more than 1% of patients:

  • Chest pain
  • Abdominal pain (stomach pain)
  • Extreme low blood pressure
  • Dizziness
  • Diarrhea
  • Headache
  • Upper respiratory infections
  • Unexplained rash

11% of patients stopped taking lisinopril for CHF because of  side effects.


Heart Attack- The following side effects occurred in more than 1% of patients:

  • Extreme low blood pressure
  • Kidney problems
17.6% of people stopped taking lisinopril post heart attack because of side effects.
According to Ask a Patient 2 other side effects include:
  • anxiety
  • irritability
  • mental fatigue 3 has a nifty list of side effects based on frequency of occurrence:


Common side effects (occur in less than in 1 out of 10 patients)

Dizziness, low blood pressure (causing dizziness especially on standing), cough, diarrhoea, being sick, headache, impaired kidney function.


Uncommon side effects (occur in less than in 1 out of 100 patients)

Changes in mood, ‘pins and needles’ or tingling, spinning sensation, taste disturbance, sleep disorder, heart attack or stroke possibly as a result of excessive low blood pressure in high risk patients, palpitations, a racing heart beat, condition causing pain, numbness, coldness and blueness of the fingers (Raynaud’s phenomenon), running nose, feeling sick, stomach pain, indigestion, reduced sexual potency in men, tiredness, weakness or loss of strength, increases in blood urea, creatinine and potassium levels, rash, itching.


Rare side effects (occur in less than in 1 out of 1,000 patients)

Decreases in haemoglobin and haematocrit, mental confusion, dry mouth, pale or red irregular raised patches with severe itching (hives), hair loss, psoriasis (itchy scaly pink patches on the elbows, knees, scalp and other parts of the body), high levels of urea and other waste products in the blood due to kidney failure, acute kidney failure, enlarged breasts in men, increases in blood levels of bilirubin, decreases in blood levels of sodium.


Very rare side effects (occur in less than 1 out of 10,000 patients, including isolated reports)

Reduced production of blood cells by the bone marrow, lymph node disease – enlargement of lymph nodes, autoimmune disease, changes in the numbers and types of your blood cells (anaemia, thrombocytopenia, eosinophilia, leucocytosis, leucopenia, neutropenia, agranulocytosis, haemolytic anaemia). If you notice increased bruising, nosebleeds, sore throats, infections, excessive tiredness, breathlessness on exertion or abnormal paleness of the skin, you should tell your doctor who may want you to have a blood test, low blood sugar levels, narrowing of the airways, sinusitis, inflammation or infection of the lungs due to an allergy (allergic alveolitis or eosinophilic pneumonia), inflammation of the liver (hepatitis) or pancreas, swelling of the intestines (intestinal angioedema), liver failure, an abnormally low or non production of urine, sweating, serious blistering skin disease (pemphigus), severe rash involving reddening, peeling and swelling of the skin that resembles severe burns (toxic epidermal necrolysis), severe form of skin rash with flushing, fever, blisters or ulcers (Stevens-Johnson Syndrome), widespread skin rash – circular, irregular red patches on the skin of the hands and arms (erythema multiforme), ‘symptom complex’ which may include one or more of the following: fever, blood vessel inflammation, muscle pain (myalgia), joint pain (arthralgia) or inflammation (arthritis), blood changes (such as positive antinuclear antibodies, elevated red blood cell sedimentation rate), sensitivity to sunlight or artificial light (e.g. sun beds), rash or other skin reactions.